Publications

Gilmore, N.K., Cowles, K., Cruz, J.M., Tran, D.T., Wong, W., Hogan, M.C., Nogueira, L. Acute inhibition of the S-nitrosoglutathione reductase delays recovery post-fatigue in isolated fast-twitch muscle. Physiological Research, Accepted for publication July 2026.

Zero, A.M., Rice, C.L., Nogueira, L. Competing effects of activation history on force and cytosolic Ca2+ in intact single mice myofibers. Pflügers Arch., 477 (3):407 – 419, 2025. Doi: 10.1007/s00424-024-03061-5. PMID: 39738587

Stevens, N.E., Loreti, M., Ramirez-Sanchez, I., Dos Reis, F.C.G., Sacco, A., Breen, E.C., Nogueira, L. Cigarette smoke exposure impairs early-stage recovery of myofiber cross-sectional area from lengthening contractions. Physiological Reports, 12(18):e70064, 2024. Doi: 10.14814/phy2.70064. PMID: 39328164

Nogueira, L, Zemljic-Harpf AE, Yusufi R, Ranjbar M, Susanto C, Tang K, Mahata SK, Jennings PA, and Breen EC. E-cigarette aerosol impairs male mouse skeletal muscle force development and prevents recovery from injury. Am J Physiol Regul Integr Comp Physiol. 323: R849-R860, 2022. Doi: 10.1152/ajpregu.00314.2021. PMID: 36250633

Nogueira, L., Gilmore, N.K., and Hogan, M.C. Fatigue-induced changes in force and intracellular cytosolic calcium transients in intact single myofibers from parvalbumin conditional knockout mice. J Appl Physiol, 132: 1041-1053, 2022. Doi: 10.1152/japplphysiol.00861.2021. PMID: 35238653

Cannon, D.T., Nogueira, L., Gutierrez-Gonzalez, A.K., Gilmore, N.K., Bigby, T.D., and Breen, E.C. Role of IL-33 receptor (ST2) deletion in diaphragm contractile and mitochondrial function in the Sugen5416/hypoxia model of pulmonary hypertension. Resp Physiol Neurobiol. 295:103783, 2021. doi: 10.1016/j.resp.2021.103783. PMID: 34508866.

Nogueira L. and Breen E.C. Invited Editorial: Cigarettes Make You Weak: RANKL/RANK Link Changes in Muscle and Bone. Am J Respir Cell Mol Biol. 64:533-535, 2021. doi: 10.1165/rcmb.2021-0098ED. PMID: 33711242

Cocksedge, S.P., Breese, B.C., Morgan, P.T., Nogueira, L., Thompson, C., Wylie, L.J., Jones, A.M., and Bailey, S.J. Influence of muscle oxygenation and nitrate-rich beetroot juice supplementation on O2 uptake kinetics and exercise tolerance. Nitric Oxide 99: 25-33, 2020. Doi: 10.1016/j.niox.2020.03.007. PMID: 32272260

Bailey, S.J., Gandra, P.G., Jones, A.M., Hogan, M.C., and Nogueira, L. Incubation with sodium nitrite attenuates fatigue development in intact single mouse fibres at physiological PO2. J. Physiol. 597: 5429-5443, 2019. doi: 10.1113/JP278494. PMID: 31541562.

Nogueira L., Trisko B.M., Lima-Rosa F.L., Jackson J., Lund-Palau H., Yamaguchi M., and Breen E.C. Cigarette smoke directly impairs skeletal muscle function through capillary regression and altered myofibre calcium kinetics in mice. J. Physiol. 596: 2901-2916, 2018. doi: 10.1113/JP275888. PMID: 29797443

Gandra, P.G., Shiah, A.A., Nogueira, L., and Hogan, M.C. A mitochondrial-targeted antioxidant improves myofilament Ca2+ sensitivity during prolonged low frequency force depression at low PO2. J. Physiol. 596: 1079-1089, 2018, doi: 10.1113/JP275470. PMID: 29334129.

Yamashita, A.M.S., Ancillotti, M.T.C., Rangel, L.P., Fontenele, M., Figueiredo-Freitas, F., Possidonio, A.C., Soares, C.P., Sorenson, M.M., Mermelstein, C., and Nogueira, L. Balance between S-nitrosylation and denitrosylation modulates myoblast proliferation independently of soluble guanylyl cyclase activation. Am J. Physiol. Cell Physiol. 313: C11–C26, 2017. doi: 10.1152/ajpcell.00140.2016. PMID: 28381519.

Figueiredo-Freitas C., Dulce R.A., Foster M.W., Liang J., Yamashita A.M., Lima-Rosa F.L., Thompson J.W., Moseley M.A., Hare J.M., Nogueira L., Sorenson M.M., and Pinto J.R. S-Nitrosylation of Sarcomeric Proteins Depresses Myofilament Ca2+-Sensitivity in Intact Cardiomyocytes. Antioxid. Redox Signal. 23: 1017-1034, 2015. doi: 10.1089/ars.2015.6275. PMID: 26421519.

Moreno-Ulloa A., Nogueira L., Rodriguez A., Barboza J., Hogan M.C., Ceballos G., Villarreal F.H., and Ramirez-Sanchez I. Recovery of Indicators of Mitochondrial Biogenesis, Oxidative Stress, and Aging With (-)-Epicatechin in Senile Mice. J. Gerontol. A Biol. Sci Med. Sci. 70: 1370-1378, 2015. doi: 10.1093/gerona/glu131. PMID: 25143004

Delavar H., Nogueira L., Wagner P.D., Hogan M.C., Metzger D., and Breen E.C. Skeletal myofiber VEGF is essential for the exercise training response in adult mice. Am. J. Physiol. Reg. Integr. Comp. Physiol. 306: R586-595, 2014. doi: 10.1152/ajpregu.00522.2013. PMID: 2452334.

Gutierrez-Salmean G., Ciaraldi T.P., Nogueira L., Barboza J., Taub P.R., Hogan M.C., Henry R.R., Meaney E., Villarreal F.H., Ceballos G., and Ramirez-Sanchez I. Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation. J. Nutr. Biochem. 25: 91-94, 2014. doi: 10.1016/j.jnutbio.2013.09.007. PMID: 24314870

Ramirez-Sanchez I., Taub P.R., Ciaraldi T.P., Nogueira L., Coe T., Perkins G., Hogan, M.C., Maisel A.S., Henry R.R., Ceballos G., and Villarreal F.H. (-)-Epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients. Int. J. Cardiol. 168:3982-90, 2013. doi: 10.1016/j.ijcard.2013.06.089. PMID: 23870648

Tang, K., Murano, G., Wagner, H., Nogueira, L., Wagner, P.D., Tang, A., Dalton, N.D., Gu, Y., Peterson, K.L., and Breen, E.C. Impaired exercise capacity and skeletal muscle function in a mouse model of pulmonary inflammation. J. Appl. Physiol. 114:1340-1350, 2013. doi: 10.1152/japplphysiol.00607.2012. PMID: 23449936.

Nogueira, L., Shiah, A., Gandra, P.G., and Hogan, M.C. Ca2+-Pumping Impairment during Repetitive Fatiguing Contractions in Single Myofibers: Role of Cross-Bridge Cycling. Am. J. Physiol. Reg. Integr. Comp. Physiol. 305: R118-R125, 2013. doi: 10.1152/ajpregu.00178.2013. PMID: 23678027.

Ramirez-Sanchez, I., Nogueira, L., Moreno, A., Murphy, A., Taub, P.R., Perkins, G., Ceballos, G., Hogan, M.C., Malek, M.L., and Villarreal, F. Stimulatory effects of the flavanol (-)-epicatechin on cardiac angiogenesis: Additive effects with exercise. J. Cardiovasc. Pharmacol. 60: 429-438, 2012. doi: 10.1097/FJC.0b013e318269ae0d. PMID: 22833114.

Gandra, P.G., Nogueira, L., and Hogan, M.C. Mitochondrial activation at the onset of contractions in isolated myofibres during successive contractile periods. J. Physiol. 590: 3597-3609, 2012. doi: 10.1113/jphysiol.2012.232405. PMID: 22711953

Nogueira, L., Ramirez-Sanchez, I., Perkins, G., Murphy, A., Taub, P.R., Ceballos, G., Villarreal, F., Hogan, M.C. and Malek, M.L. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J. Physiol. 589: 4615-4631, 2011. doi: 10.1113/jphysiol.2011.209924. PMID: 21788351

Sun, Q.A., Hess, D.T., Nogueira, L., Yong, S., Bowles, D.E., Eu, J., Laurita, K.R., Meissner, G., and Stamler, J.S. Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4. Proc. Natl. Acad. Sci. USA. 108: 16098-16103, 2011. doi: 10.1073/pnas.1109546108. PMID: 21896730

Zuo, L., Nogueira, L., and Hogan, M.C. Reactive oxygen species formation during tetanic contractions in single isolated Xenopus myofibers. J. Appl. Physiol. 111: 898-904, 2011. doi: 10.1152/japplphysiol.00398.2011. PMID: 21700897

Zuo, L., Nogueira, L., and Hogan, M.C. Effect of pulmonary TNF-α overexpression on mouse isolated skeletal muscle function. Am. J. Physiol. Reg. Integr. Comp. Physiol. 301: R1025-R1031, 2011. doi: 10.1152/ajpregu.00126.2011. PMID: 21697519

Nogueira, L., and Hogan, M.C. Phenol increases intracellular [Ca2+] during twitch contractions in intact Xenopus skeletal myofibers. J. Appl. Physiol. 109: 1384-1393, 2010. doi: 10.1152/japplphysiol.00660.2010. PMID: 20724558

Nogueira, L., Figueiredo-Freitas, C., Casimiro-Lopes, G., Magdesian, M.H., Assreuy, J., and Sorenson, M.M. Myosin is reversibly inhibited by S-nitrosylation. Biochem. J. 424: 221-231, 2009. doi: 10.1042/BJ20091144. PMID: 19747166

Forrester, M.T., Thompson, J.W., Foster, M.W., Nogueira, L., Moseley, M.A., and Stamler, J.S. Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture. Nature Biotechnol. 27: 557-559, 2009. doi: 10.1038/nbt.1545. PMID: 19483679